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Monday, October 5, 2020 | History

2 edition of Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia found in the catalog.

Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia

National Institutes of Health (U.S.)

Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia

by National Institutes of Health (U.S.)

  • 298 Want to read
  • 10 Currently reading

Published by [Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health] in Bethesda, Md .
Written in English

    Subjects:
  • Amyotrophic lateral sclerosis,
  • Parkinson"s disease

  • Edition Notes

    StatementPaul M. Hoffman ... [et al.]
    ContributionsHoffman, Paul M
    The Physical Object
    Paginationp. [680-685] :
    Number of Pages685
    ID Numbers
    Open LibraryOL14904048M

    Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias Michael J. Strong Over the past ten years, there has been an increasing recognition that syndromes of frontotemporal dysfunction (FTD) are a common occurrence in patients with amyotrophic lateral sclerosis (ALS).   Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia by National Institutes of Health (U.S.) First published in

    Hoffman PM, Robbins DS. Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia. Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ, Gajdusek DC. Histocompatibility. Cellular Immunity in Guamanians with Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia AMYOTROPHIC lateral sclerosis and Parkinsonism-dementia, This is an excellent book, and I.

    Humoral immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia. Hoffman PM, Robbins DS, Oldstone MB, Gibbs CJ, Gajdusek DC Defective immunoregulation in .   Cell damage and/or genome instability with type 1 diabetes and patients with type 2 diabetes. with aging promote senescence of EPCs probably Tepper et al. (20) showed that EPCs from patients with through increase in oxidative stress. Gajdusek DCHumoral immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia. Ann.


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Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia by National Institutes of Health (U.S.) Download PDF EPUB FB2

Abstract. To test the hypothesis that host resistance factors may be abnormal in Guamanians in whom amyotrophic lateral sclerosis and Parkinsonism-dementia develop, cellular immunity was evaluated Cited by:   Guamanian patients with amyotrophic lateral sclerosis and diminished cellular immunity had an increased frequency of HLA-Bw35 (P less than ) and shorter mean duration of disease (P less than ) than those with normal cellular immunity.

In Parkinsonism dementia diminished cellular immunity was less strongly associated with HLA-BW35 (P less than ) and was not Cited by:   Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia. Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ Jr, Gajdusek DC N.

Engl. Med., (13)Cited by: Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ, Jr, Gajdusek DC. Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia. N Engl J Med. Sep 28; (13)– Jokelainen M, Wikström J, Palo J. Effect of birthplace on the development of amyotrophic lateral sclerosis and multiple by: Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ, Gajdusek C () Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia.

N Cited by: 7. Gajudsek DC, Gibbs CJ Jr, Hoffman PM, et al: Cellular immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonismdementia. N Engl J Med ; Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ Jr, Gajdusek DC () Cellular immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia.

N Engl J Med – PubMed Google Scholar. 1. Introduction. Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease which primarily affects upper and lower motor neurons leading to generalized muscle weakness, progressive paralysis, respiratory depression and death within 3–5 years.

Multiple pathogenic mechanisms, including excitotoxicity, oxidative stress, mitochondrial dysfunction, axonal transport.

Hoffman, P.M., D.S. Robbins, M.T. Nolte, C.J. Gibbs, Jr. and D.C. Gajdusek () Cellular immunity in Guamanians with amy- otrophic lateral sclerosis and. Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia.

Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ, Gajdusek DC N Engl J Med, (13), 01 Sep   Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder character‐ ized by death of pyramidal neurons in the motor cortex (upper motor neurons) and motor.

Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ, Jr, Gajdusek DC. Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia. N Engl J Med. Sep 28; (13)– Isaković K, Janković BD.

Neuro-endocrine correlates of immune response. Changes in the lymphatic organs of brain-lesioned rats. Postencephalitic Parkinson's disease, amyotrophic lateral sclerosis on Guam and influenza revisited: focusing on neurofibrillary tangles and the trail of tau D.C.

GajdusekCellular immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia. P M Hoffman's 59 research works with 1, citations and 1, reads, including: Voltage-gated potassium channels in multiple sclerosis: Overview and new implications for treatment of central.

Hoffman PM, Robbins DS, Oldstone MBA, et al: Humoral immunity in Guamanians with amyotrophic lateral sclerosis and parkinsonism-dementia. Ann Neurol ; Crossref. Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ Jr, Gajdusek DC () Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia.

N Engl J Med (13)– PubMed CrossRef Google Scholar. Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis Patient Therapeutic Trial Transfer Factor Motor Neuron Disease These keywords were added by machine and not by the authors.

This process is experimental and the keywords may be updated as the learning algorithm improves. Amyotrophic lateral sclerosis/parkinsonism-dementia complex of the Kii peninsula (Kii ALS/PDC) is a neurodegenerative disorder endemic to natives in the southern coast area of the Kii peninsula of.

Hoffman PM, Robbins DS, Nolte MJ, et al: Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia. N Engl J Med ; Crossref. Lymphocytes from Guamanians with amyotrophic lateral sclerosis or parkinsonismdementia and from individuals in good health were studied to determine the possible role of cellular immunity in the pathogenesis of these diseases, which occur at extraordinarily high rates on Guam.

Cell Immunol. Jun; 61 (1)– Hoffman PM, Robbins DS, Nolte MT, Gibbs CJ, Jr, Gajdusek DC. Cellular immunity in Guamanians with amyotrophic lateral sclerosis and Parkinsonism-dementia.

N Engl J Med. Sep 28; (13)– Isaković K, Janković BD. Neuro-endocrine correlates of immune response. II.Innate neuroimmune dysfunction is a pathobiological feature of amyotrophic lateral sclerosis (ALS).

However, links, if any, between disease and adaptive immunity are poorly understood.E. Kott, E. Livni, R. Zamir, and A.

Kuritzky, Amyotrophic lateral sclerosis: cell-mediated immunity to poliovirus and basic myelin protein in patients with high frequency of HLA-BW35, Neurology, – (). Google Scholar.